mise à jour du 10 juillet 2003
Medicina (B Aires)
2003; 63(2):137-9
Bostezo y epilepsia del lobulo temporal
Salomon Muchnik, Samuel Finkielman, Gullermo Semeniuk,
Maria Inès de Aguirre
Instituto de Investigaciones Médicas Alfredo Lanari, Facultad de Medicina, Universidad de Buenos Aires, Servicio de Neurologia I.D.I.M Alfredo Lanari


Yawning and temporal tobe epilepsy
Temporal lobe epilepsy is a partial epileptic disorder in which mesial structures are responsible for the principal ictal symptoms. Its chacteristic feature is the recurrence of simple and complex partial seizures, associated with postictal confusion and anmesia of the event.
The facilitating effect of NREM sleep on the propagation of the seizure, as well as the sleep, abnormalities provoked by epilepsy were evident in our two patients. Yawning is a physiological reflex induced by arousal and drowsiness and may appear in different neurological conditions. Its relation with epilepsy of limbic origin has been rarely reported.
We describe in one ninety five year old male patient, the occurrence of yawning followed by complex partial seizure during a state of drowsiness. His EEG showed independent bilateral interictal loci of temporal sharp waves and after being medicated with carbamazepine 400mg/day, the episode did not recur. Another patient a seventeen year old female, displayed complex partial seizures and secondarily generalized seizures with yawnig during the posictal period, after naps. The EEG was normal and her polysomnography showed bilateral synchronous temporal spikes and slow waves with secondanly generalization during stage 2 of NREM sleep that produce paroxysmal microarousals and increased stages 1 and 2 of NREM sleep and REM sleep diminished. After being medicated with divalproex sodium 750 mg/day, she suffered no futher seizures.
Temporal lobe epilepsy, sleep wake cycles and yawning seem not only to share the same anatomic structures but also the same neurochemical mechanisms. The fact that endogenous opiods are considered as part of a protective system that stop and prevent seizures may allow us to, postulate that yawning would be the expression of the endogenous opiods induced mechanisms, that stop and prevent the recurrence of the temporal lobe epilepsy. Another view may this is just a particular form of temporal lobe epilepsy.
Bostezo y epilepsia del lobulo temporal pdf file
 Bostezos y epilepsia del lóbulo temporal
Yawning and temporal lobe epilepsy
Bâillements et épilepsie du lobe temporal
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Yawning and epilepsy L Goldie
Bostezo S Muchnik, S Finkielman, G Semeniuk, Maria Inès de Aguirre
Bostezo y epilepsia del lobulo temporal S Muchnik, S Finkielman, G Semeniuk, Maria Inès de Aguirre
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